In a study investigating the influence of the SOX17 protein in esophageal squamous cell carcinoma (ESCC), it was observed that human MALAT1 contains an SRY element in its promoter, which is associated with SOX17 via TF binding [44], and then the authors suggested that SOX17 significantly limits MALAT1 expression. Here, TF is linked to esophageal squamous cell carcinoma.