A further study on correlations between insertion–deletions (InDels) in the fragile histidine triad (FHIT) gene and lactation traits in Xinjiang brown cattle revealed significant associations between eight InDels in the gene and lactation traits [11], while an investigation using pyrosequencing showed that methylation of the promoter regions of the FHIT gene and protein inhibitor of activated STAT1 and PIAS1 genes in mastitis-affected cows were higher and lower, respectively, than those in the control group [12]. Here, FHIT is linked to mastitis.