Classical-like EDS (clEDS) is a rare type of autosomal recessive EDS that is further categorized based on genetic causes: classical-like EDS type 1 (clEDS1) MIM #606408 is associated with variants in the TNXB gene [1], and classical-like EDS type 2 (clEDS2) MIM #618000 is associated with variants in the AEBP1 gene [2,3]. This evidence concerns the gene AEBP1 and Ehlers-Danlos syndrome.