After adjusting for the risk factors (age, sex, BMI, WC, HDL, TG, diabetes mellitus, and hypertension) (Table S3), the association of PNPLA3 rs738409 C>G, MASLD without liver fibrosis was positively correlated with the GG genotype (OR = 9.085, 95%CI 1.073–76.885, p = 0.043), while the CG genotype did not show statistical significance. The gene discussed is PNPLA3; the disease is diabetes mellitus.