TGFB1 and posterior cortical atrophy: In PCa, ERG activates proteins, such as WNT, EZH2, TGFB, and SOX9 [46,47], and is known to induce NF-κB-mediated transcription through phosphorylation of NF-κB p65 [48], thus playing an important role in inducing the invasion of PCa cells.