The diagnostic accuracy of the seven-gene signature (Down—FCGBP and KLF12; Up—FCGR1B, ANKRD22, CARD17, IFITM3, and TNFAIP6) showed AUC values between 0.84 and 1 with a sensitivity of 80–100% and specificity of 80–95%, which can differentiate between active TB and LTBI [66]. Here, ANKRD22 is linked to tuberculosis.