CD4 and tuberculosis: However, TB patients showed significantly lower numbers of B-cells, cDCs, CD4+ T-cells, CD4+ Tcm, CD4+ Tem, CD4+ memory T-cells, CD4+ naive T-cells, CD8+ T-cells, CD8+ Tcm, CD8+ Tem, class-switched memory B-cells, iDCs, megakaryocyte–erythroid progenitor (MEPs), mast cells, memory B-cells, naive B-cells, NK cells, pro B-cells, and Th1 cells as compared to HCs (Figure 3).