To further confirm the relationship between nine EV-related DEGs (SERPINA1, TNFAIP6, MAPK14, STAT1, ITGA2B, VAMP5, CTSL, CEACAM1, and PLAUR) and TB, we determined the correlation, which showed that these genes interacted synergistically and were significantly upregulated in TB patients. This evidence concerns the gene VAMP5 and tuberculosis.