Indeed, deletions and duplications of the CHRNA7 gene have been reported in patients with neurological phenotypes such as cognitive deficits, epilepsy, language disorders, abnormal behaviour, ASD, ADHD or attention deficit disorder, mood disorders, and schizophrenia, with varying degrees of penetrance and severity, suggesting that the human brain is sensitive to CHRNA7 dosage [63]. This evidence concerns the gene CHRNA7 and epilepsy.