Hence, the SNPs with high OR values showing a positive association of AMD with cataract included C3 (rs11569415 with OR 1.123), followed by HERPUD1;CETP (rs247617 with OR 1.097) and RP11-1149O23.3 (rs13278062 with OR 1.083). Here, HERPUD1 is linked to age-related macular degeneration.