SDHA and von Hippel-Lindau disease: In the literature, up to 30% of PPGL patients report a positive family history with an identifiable hereditary syndrome, including Von Hippel Lindau disease (VHL), multiple endocrine neoplasia type 2 (MEN 2), type 1 neurofibromatosis (NF1) and familial PPGL syndrome that occur secondary to SDHA/B/C/D germline gene mutations [13,14].