The PGL diagnoses were as follows: five patients presented PPGL-related symptoms including hypertension resistant to medical treatment, diaphoresis, migraine and palpitations; two patients were diagnosed during diagnostic imaging for unspecific abdominal pain; four patients were diagnosed during screening for genetic syndromes (two patients affected by Von Hippel Lindau syndrome and another two patients with SDH germline mutation); and the last two patients were diagnosed with PGL during follow-up for neoplastic disease (breast tumor and Hodgkin’s lymphoma). The gene discussed is SDHB; the disease is hypertensive disorder.