GSTM1 and colorectal carcinoma: Indeed, when the analysis of the effect of GST genetic variants on CRC patients’ overall survival was conducted using Model 1 (adjustment to age and sex), the obtained results clearly indicated that the risk of mortality was significantly higher (HR 1.81, 95% CI 1.22–2.68, p = 0.003) in individuals lacking the GSTM1 protein when compared to those with the intact protein presence.