Some other previous studies on galectin-3 have shown that galectin-3 can be used as a diagnostic or prognostic biomarker for heart failure, renal failure, and some types of cancer (thyroid carcinoma, hepatocellular carcinoma (HCC), endometrial tumor, osteosarcoma, etc.)[12]. This evidence concerns the gene LGALS3 and thyroid gland carcinoma.