Photo-documentation of CAM tumors developing from inoculated RB cells (Figure 10a) and quantification of tumor weight (Figure 10b) and size (Figure 10c) revealed that PTPRE-depleted, etoposide-resistant RB cells develop significantly smaller tumors (Figure 10a,c) than control cells, while in the case of Y79_Etop cells, there was also significantly lower tumor weight (Figure 10b). The gene discussed is PTPRE; the disease is neoplasm.