Regardless of antibiotic treatment, median hBD1 expression was significantly increased in all tumor tissues, 2.62-fold in BC AB0 (p = 0.014), 2.54-fold in the BC AB6 (p = 0.041), 2.57-fold in the FQ (p = 0.047), 2.62-fold (p = 0.014) in the FOS, and 2.59-fold (p = 0.015) in the BL group. The gene discussed is DEFB1; the disease is neoplasm.