By comparing these signaling pathways with KEGG pathways (map05210), five signaling pathways play crucial roles in influencing CRC: the Wnt signaling pathway, PI3K/AKT/mTOR signaling pathway, MAPK signaling pathway, TGF-β signaling pathway, and p53 signaling pathway [9,13]. This evidence concerns the gene MTOR and colorectal carcinoma.