ILCs of the ILC22 type include NKp46(+) and lymphoid tissue-inducer (LTi)-like subsets that express AHR and protect the intestinal mucosa from infection by secreting IL-22 that acts on mucosal epithelial cells, inducing their survival, proliferation, and secretion of antimicrobial peptides [55,58,59,60]. The gene discussed is IL22; the disease is infection.