CGRP is involved in the motility stimulation (increase by 30–40%), migration, and invasion of tumor cells, together with other neuropeptides such as adrenomedullin and calcitonin, and seems to cooperate within the metastasis process [20,31,32]; the process seems to be related to or a component of the epithelial–mesenchymal transition, which is involved in the progression of carcinomas at different locations [33,34]. This evidence concerns the gene CALCA and carcinoma.