We divided the FSS of CGRP into low and high levels, and, according to the clinicopathological characteristics of patients with CRC, we observed that the increased levels of CGRP are significantly associated with age (χ2 = 4.7, p = 0.03), TNM stage (χ2 = 6.686, p = 0.042), and tumor pathological grade (χ2 = 7.7, p = 0.021) at the statistical limit of significance for tumor extension (χ2 = 5.534, p = 0.052) and are not significantly associated with age, lymph node, or distant metastasis (Table 4). This evidence concerns the gene CALCA and colorectal carcinoma.