Consequently, demethylated LncRNA GLCC1 stabilizes the IGF2 mRNA binding protein 1 (IGF2BP1)-c-Myc complex, with downstream activation of the tumour-promoting c-Myc-associated signalling pathway translating into enhanced leukaemia aggressiveness and Ara-c chemoresistance [70]. The gene discussed is IGF2BP1; the disease is neoplasm.