ANGPT1 and endometriosis: Additionally, estrogens and hypoxia-related factors [angiogenin (ANG), angiopoietin 1 (ANGPT1), or vascular endothelial growth factor (VEGF)] have been suggested to promote endometriosis-related EMT via MAPK/ERK, PI3K/AKT, or β-catenin cascades [47,48].