This is of interest as the Mycobacterium tuberculosis B-29 peptide (VLRIVNEPTAAALAY) is believed to generate HSP-specific Tregs that suppress arthritis through the cross-recognition of human HSP homologues [36], and this is one aspect of IRL201805 we are aiming to assess in future studies to elucidate its mode of action further. The gene discussed is HSP90B2P; the disease is arthritic joint disease.