IGFBP2 and ataxia telangiectasia: IGFBP-2 was significantly increased in serum from CE and ESUS patients compared to those with AT etiology (median [IQR]: 395.7 [250.4–672.6] ng/mL CE vs. 226.1 [142.8–393.0] ng/mL AT, p < 0.05) and vs. 346.6 [295.7–670.2] ng/mL ESUS, p < 0.05, Figure 5A).