In an independent cohort of hypertensive patients (Table S5), those with AF (n = 78) had significantly higher circulating levels of IGFBP-2 compared to those without AF (n = 20) (median [IQR]: 438.5 [337.5–565.6] ng/mL vs. 115.7 [97.1–164.0] ng/mL, p < 0.001). This evidence concerns the gene IGFBP2 and atrial fibrillation.