Eosinophils may promote tumour angiogenesis by the secretion of angiogenic factors, including the vascular endothelial growth factor (VEGF) and fibroblast growth factor-2 (FGF-2), granulocyte-macrophage colony-stimulating factor (GMCSF), and IL-8 [87,88,89]. This evidence concerns the gene FGF2 and neoplasm.