CML is a leukemia resulting from the translocation t(9; 22) (q34; q11) [70], which leads to the formation of the Philadelphia chromosome containing the breakpoint cluster region—v-abl Abelson murine leukemia viral oncogene homolog 1 (BCR-ABL1) fusion gene [86]. Here, ABL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.