GALR2 and familial pancreatic carcinoma: For example, in Molm-14 cells, the top 20 upregulated genes included GALR2 (encodes Galanin receptor 2, a G-protein-coupled receptor that decreased proliferation and induced apoptosis in human head and neck cancer cells and human neuroblastoma cells [35,36]) and CYGB (a member of the globin superfamily, which was shown to reduce proliferation in human breast cancer cells, human colorectal cancer cells, human pancreatic cancer and human lung adenocarcinoma, as well as apoptosis in human breast cancer cells [37,38,39,40]).