PD is a chronic, heterogeneous, and progressive neurodegenerative disease pathologically characterized by intracellular aggregates of α-synuclein (α-syn) in Lewy bodies (LBs) and neurites and loss of dopaminergic (DA) neurons in the substantia nigra (SN), which is responsible for the onset of motor symptoms [4,5]. Here, SNCA is linked to Parkinson disease.