In a retrospective study of a Parkinsonism cohort involving six PSP patients, the apparent transverse relaxation rate (R2*) and QSM measurement at an average interval of 23.6 months prior to death were correlated with post-mortem neuromelanin-positive neuron, α-synuclein, tau, and glial density (% area). This evidence concerns the gene SNCA and Parkinson disease.