MAPT and Alzheimer disease: Evaluating Aβ-CSF-positive cognitively unimpaired versus impaired AD patients, quantitative susceptibility mapping (QSM) values of the cortical and inferior temporal gyrus (ITG), as well as their tau-SUVR uptake levels were found to be increased, with a negative correlation between the QSM signal in the ITG and global cognition, as quantified by the mini-mental state examination (MMSE) [19].