The findings of the presented papers indicate the significant association between the CXCL12, CXCR4, CXCL8/CXCR2, M-CSF, SCF, MMP-2, MMP-9, ADAM17, ADAM9, ADAMTS-6, and CLDN7 levels and tumor stages of OC. This evidence concerns the gene CXCR2 and neoplasm.