NFKBIE and cancer: This cluster is also composed of the protein coding genes’ NFKB Inhibitor Epsilon (NFKBIE) inhibitor of the NF-kappa-B signaling pathway associated with the inflammatory process in cancer [81,82], the Interleukin 2 Receptor Subunit Beta (IL2RB), and Cbp/P300 Interacting Transactivator With Glu/Asp Rich Carboxy-Terminal Domain 4 (CITED4), which are the regulators of the T-cell immune response and gene transcription, respectively [83,84], both, in cases of high expression, present a poor prognosis and are related to metastasis development.