Several gene modules that are enriched in genes from the ploidy-downregulated gene signature for MSC and cancer cells (425 gene set, Supplementary Table S3, Figure 3) are also overrepresented among common ploidy-downregulated genes for CP (244 gene set, Supplementary Table S11, Supplementary Figure S3) and young CARD (183 gene set, Supplementary Table S12, Supplementary Figure S4). Here, CP is linked to cancer.