MET and neoplasm: According to the location of the neoplasm, cell infusions have been performed directly into the hepatic artery in colorectal cancer [206], breast cancer using CAR anti-c Met T cells [207], intracavitary and intraventricular in glioblastomas where it was observed that while the first option managed to reduce tumor diameter, the second managed to dramatically reduce the size of all intracranial tumors [208], without presenting relevant toxicities in any of the registered cases.