After analyzing the influence of MS occurence, binary logistic regression revealed that STAT4 rs7601754 was statistically significantly associated with 1.9-fold increased odds of MS occurrence in the dominant model (OR = 1.912; 95% CI: 1.237–2.954; p = 0.004) and each G allele was associated with 1.7-fold increased odds of MS occurrence in the additive model (OR = 1.732; 95% CI: 1.193–2.516; p = 0.004), which were the best fit according to the AIC value, even after Bonferroni correction. Here, STAT4 is linked to myeloid sarcoma.