Nevertheless, authors must be cautious when measuring and interpreting results based on sHLA-G concentrations, since this antigen expression could vary according to certain pathologies, like Systemic Lupus Erythematosus (SLE) or Antiphospholipid Syndrome (APS), and even in response to certain medications [71,72,73]. The gene discussed is HLA-G; the disease is systemic lupus erythematosus.