Taking into consideration the fact that high concentrations of specific Toll-like receptors (TLR) such as TLR-3, TLR-4, TLR-7, and TLR-9 have been discovered in the thymus of myasthenic patients and that, through these receptors of the innate immune system, the dendritic cells mature and are capable of initiating adaptative immune responses, one can conclude that the key between chronic inflammation/infection and autoimmunity resides in the intricate interactions between the adaptive and the innate immune systems [58,59,60]. This evidence concerns the gene TLR9 and Autoimmunity.