TGFA and myasthenia gravis: The chronic inflammation theory becomes even more plausible in the context that inflammation plays a significant role in the pathogenesis of MG, as it is supported by the finding that several proteins known to be associated with inflammation (such as matrix metalloproteinase 10, transforming growth factor alpha, and extracellular newly identified receptor for advanced glycation end-products binding protein) are found to be elevated in the sera of myasthenic patients [45].