PTX3 and eosinophilic granulomatosis with polyangiitis: In another study on a total of 101 patients with either GPA, EGPA or MPA, Padoan et al. reported that the presence of anti-PTX3 antibodies in the serum was associated with a lower prevalence of renal, ENT and systemic manifestations and was particularly useful as a biomarker in subjects with EGPA [76].