-Decreasing LDL cholesterol levels overall. Elevated LDL cholesterol is a risk factor for cardiovascular diseases, including atherosclerosis and heart disease.-Reducing the production of pro-inflammatory cytokines (such as TNF-α and IL-6) in blood vessels and tissues.-Enhancing nitric oxide production promotes vasodilation and maintains healthy blood flow.-By maintaining cholesterol homeostasis, campesterol contributes to cardiovascular health. The gene discussed is TNF; the disease is atherosclerosis.