NFKB1 and periodontitis: Recently, analyses showed that bacteria such as Porphyromonas gingivalis, which are present in periodontitis, can also be identified in atheromas and are associated with the activation of the NF-κB-BMAL1-NF-κB signaling loop [49], while there might be a relation of periodontitis with myocardial infarction and major adverse cardiovascular events [50].