Thus, similarly as in the prefibrotic context, ANC, ALC and platelet count were further evaluated in the final prognostic model that was additionally adjusted for age ≥ 60 years, history of thrombosis, sex, JAK2 mutational status, presence of classic cardiovascular risk factors and chronic kidney disease, and which is presented in Table 4. The gene discussed is JAK2; the disease is deep vein thrombosis.