MKI67 and neoplasm: At the gingival level, several variables can be used to evaluate the impact of rh-BMP-2, e.g., the vascular endothelial growth factors (VEGF) in the epithelium and connective tissue graft, as well as the Ki-67 protein, which has been widely used as a proliferation marker [19,20,21,22,23] Antibodies against Ki-67 have been used as prognostic factors in the diagnosis of several types of neoplasm [18,23].