FAS and neuroblastoma: KEGG pathway analysis of FAS pathways in HR and LR NB patients revealed that while the de novo FAS pathway genes were uniquely enriched in HR patients, the majority of ω3 precursor α-linolenic acid (ALA, 18:3ω3) and ω6 precursor LA metabolism genes, represented by UFAS, were suppressed (Figure 5h).