In 45 patients with gynecological cancers the most commonly altered genes were TP53 (n = 22/45, 48.9%), ARID1A (n = 6/45, 13.3%), BRCA1/2 (n = 6/45, 13.3%), and KRAS (n = 5/45, 11.1%) (Figure 2a and Supplementary Table S5). The gene discussed is BRCA1; the disease is female reproductive organ cancer.