The MD values were significantly higher in patients with astrocytomas than in those with glioblastomas (IDH-mut vs. IDH-wt groups: 1.47 ± 0.21 × 10−3 vs. 1.24 ± 0.21 × 10−3; p < 0.0001; Figure 1C); the cut-off value, AUC, sensitivity, and specificity were 1.28, 0.78, 74%, and 80%, respectively (Figure 1D). Here, IDH1 is linked to glioblastoma.