In their second study, Yang et al. used HepG2, Huh7, and SMMC-7721 HCC cell lines, developing oxaliplatin-resistant cell lines via increasing the exposure to oxaliplatin in several time intervals, utilizing parental HCC as controls, aiming to associate Cx32 expression with EMT induction and chemosensitivity to oxaliplatin in HCC cells [59]. The gene discussed is GJB1; the disease is hepatocellular carcinoma.