GJB1 and metabolic dysfunction-associated steatohepatitis: Sagawa et al., using mouse models, specifically Cx32 dominant negative transgenic (Cx32ΔTg) and wild-type (Wt) mouse models, which were given diethylnitrosamine and fed methionine-choline-deficient diet (MCDD) or MCDD with luteolin for 12 weeks, as well as liver tissue samples for the histologic analysis of non-alcoholic steatohepatitis (NASH), aimed to define the role of Cx32 and the chemopreventive effect of luteolin, an antioxidant flavonoid, on the progression of NASH and NASH-related hepatocarcinogenesis [74].