IGF1R, the insulin-like growth factor (IGF) receptor, belongs to the receptor-type tyrosine kinase family, the signaling axis of which is critical for the onset and progression of many tumors; it has been validated as the miR-378a target in glioma, hepatocarcinoma, and rhabdomyosarcoma [40,41,42];. The gene discussed is IGF1R; the disease is central nervous system cancer.