Furthermore, miR-378a has been demonstrated to contribute to the mechanism of action of the lncRNA OIP5-AS1, whose oncogenic effect has been demonstrated in vitro and in vivo; in fact, it was verified that OIP5-AS1 was able to sponge miR-378a-3p, thus reverting miRNA antiproliferative activity in lung cancer cells [48]. Here, OIP5 is linked to lung carcinoma.