Overall, young age (i.e., <60 years old) was strongly associated with IDH mutation (p = 4.8 × 10−6), male sex (p = 0.02), and longer OS (p = 6.0 × 10−5), confirming that our series is representative of the usual grade 4 astrocytoma epidemiology. The gene discussed is IDH1; the disease is astrocytoma (excluding glioblastoma).