In examined A549 cells, its inhibition was correlated with the increased rate of gefitinib-induced apoptosis of malignant cells, suggesting that stabilizing mitogen-inducible gene 6 (MIG6) by suppressing DNAJB1 levels could increase the sensitivity of lung cancer cells to EGFR-targeting tyrosine kinase inhibitors like gefitinib [247]. The gene discussed is DNAJB1; the disease is lung carcinoma.