Tumor-infiltrating lymphocytes (TILs) with cytotoxic CD8+ and regulatory FOXP3+ expression, microsatellite instability, high tumor mutational burden, and the expression of immune checkpoint molecules like programed death ligand 1 (PD-L1) are some of the main factors that contribute to TNBC’s immunogenicity [171]. This evidence concerns the gene CD274 and neoplasm.