Additionally, genes implicated in the remodeling of the TME, including members of the collagen family (COL1A, COL1A2, COL3A1, COL5A2) [38], fibronectin (FN1) [52], and SFRP4 [47], were identified as putative markers of PCa progression. The gene discussed is COL1A2; the disease is posterior cortical atrophy.