The proteins encoded by these 11 DEGs, COL1A1, WNT2B, IRF5, SYK, BMP8A, NTRK1, JAG1, DNMT1, CD14, GAS1, and SIGIRR, collectively present a set of functional properties that may be integral in limiting the immune response within the TME of PCa when an EMT transcriptional program is regulated by ZEB1. Here, ZEB1 is linked to posterior cortical atrophy.