MME and neoplasm: Some data suggest an increase in tumoural CD10 expression in advanced CRC tumour stages, based on Duke’s classification [14,19], lymphatic invasion [20], lymph node metastasis [9,14,20], and liver metastasis [8,15,16,17,18], while others found no association with histopathological features such as tumour size or invasion depth [9,15,20,21,22], TNM staging [9], or lymph node or distant metastasis [9,15,21,22,28].