Increased levels of fucosylated hemopexin, fetuin A, alpha 1 antitrypsin, ceruloplasmin, serum paraoxoanase 1, and histidine rich-glycoprotein have all been observed in patients with HCC and correlated with increased fucosylation in HCC biopsied tissue [50,52,55,56,57,58]. This evidence concerns the gene SERPINA1 and hepatocellular carcinoma.