KCNJ2 and Andersen-Tawil syndrome: We reported a three-generation family with six living individuals affected by ATS and a broad spectrum of phenotypic presentations, in which genetic investigation using whole exome sequencing (WES) identified the previously reported heterozygous loss-of-function (LoF) variant in KCNJ2 (NM_000891.2: c.652C>T, p. Arg218Trp).