The CBD-induced cytotoxicity in CL-1 T-cell lymphoma can potentially be mediated through receptors other than CB1 and CB2, as CBD has been shown in other studies to activate the transient receptor potential vanilloid subtype 1 (TRPV1), G protein-coupled receptor GPR55, the 5-HT1a receptor, and the α3 and α1 glycine receptors [56]. This evidence concerns the gene HTR1A and T-cell non-Hodgkin lymphoma.